Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

FAK (Ab 576 / 577) Antibody

Product Specifications

Background

Non-receptor protein-tyrosine kinase implicated in signaling pathways involved in cell motility, proliferation and apoptosis. Activated by tyrosine-phosphorylation in response to either integrin clustering induced by cell adhesion or antibody cross-linking, or via G-protein coupled receptor (GPCR) occupancy by ligands such as bombesin or lysophosphatidic acid, or via LDL receptor occupancy. Plays a potential role in oncogenic transformations resulting in increased kinase activity.

NCBI Gene ID

5747

Swiss Prot

Q05397

Accession Number

NP_005598.3

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

FAK (Ab-576/577) antibody was raised against a peptide sequence around aa.574~578/575~579 (T-Y-Y-K-A) derived from Human FAK.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Concentration

1 mg/mL

Buffer

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store antibody at -20˚ C for up to one year.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=79-433

Calculated Molecular Weight

125 kDa

Specificity

This antibody detects endogenous level of total FAK protein.

Applications Notes

Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100

Symbol

PTK2

NCBI Official Name

Protein tyrosine kinase 2

NCBI Organism

Homo sapiens

Background Reference 01

Parsons, J. T. et al. (2000) Oncogene 19, 5606-5613. Schaller, M. D. et al. (1994) Mol. Cell. Biol. 14, 1680-1688. Chen, H. C. et al. (1996) J. Biol. Chem. 271, 26329-26334. Calalb, M. B. et al. (1995) Mol. Cell. Biol. 15, 954-963.

Other Product Names

FAK, FADK, FAK1, FRNK, PPP1R71, p125FAK, pp125FAK, JTK2, TKF, FADK 1, PTK2

Tested Applications

WB, IHC

Protein ID

27886593

Physical Properties

Liquid

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

IFluor® 660 Anti-human CD20 Antibody *HI20a*
102010G0-AAT 100 Tests

IFluor® 660 Anti-human CD20 Antibody *HI20a*

Ask
View Details
Rabbit Monoclonal CRELD1 Antibody (116) [Alexa Fluor 700]
NBP2-90218AF700 0.1 mL

Rabbit Monoclonal CRELD1 Antibody (116) [Alexa Fluor 700]

Ask
View Details
KCNJ15 Antibody
MBS8591212-01 0.1 mg

KCNJ15 Antibody

Ask
View Details
KCNJ15 Antibody
MBS8591212-02 0.1 mL (AF405L)

KCNJ15 Antibody

Ask
View Details
KCNJ15 Antibody
MBS8591212-03 0.1 mL (AF405S)

KCNJ15 Antibody

Ask
View Details
KCNJ15 Antibody
MBS8591212-04 0.1 mL (AF610)

KCNJ15 Antibody

Ask
View Details