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SHP 1 (Ab 536) Antibody

Product Specifications

Background

Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus.

NCBI Gene ID

5777

Swiss Prot

P29350

Accession Number

NP_002822.2

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

SHP-1 (Ab-536) antibody was raised against a peptide sequence around aa.534~538 (S-E-Y-G-N) derived from Human SHP-1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Concentration

1 mg/mL

Buffer

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store antibody at -20˚ C for up to one year.

Calculated Molecular Weight

68 kDa

Specificity

This antibody detects endogenous level of total SHP-1 protein.

Applications Notes

Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200

Symbol

PTPN6

NCBI Official Name

Protein tyrosine phosphatase, non-receptor type 6

NCBI Organism

Homo sapiens

Background Reference 01

Migone TS, et al. (1998) Proc Natl Acad Sci USA; 95 (7) : 3845-3850. Timms JF, et al. (1998) Mol Cell Biol; 18 (7) : 3838-3850. Kanagasundaram V, et al. (1999) Mol Cell Biol; 19 (6) : 4079-4092. Hauck CR, et al. (1999) Infect Immun; 67 (10) : 5490-5494.

Other Product Names

HCP, HCPH, SHP1, SHP-1, HPTP1C, PTP-1C, SHP-1L, SH-PTP1, BLIMP1, 70Z-SHP, EC 3.1.3.48, HCP, Hematopoietic cell protein-tyrosine phosphatase

Tested Applications

WB, IHC, IF

Protein ID

18104989

Physical Properties

Liquid

Frequently Asked Questions

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