Keratin 18 (Ab 33) Antibody

Product Specifications

Background

KRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. utations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene.

NCBI Gene ID

3875

Swiss Prot

P05783

Accession Number

NP_000215.1

Host

Rabbit

Reactivity

Human

Immunogen

Keratin 18 (Ab-33) antibody was raised against a peptide sequence around aa.31~35 (A-A-S-V-Y) derived from Human Keratin 18 (CK18) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Concentration

1 mg/mL

Buffer

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store antibody at -20˚ C for up to one year.

Calculated Molecular Weight

46 kDa

Specificity

This antibody detects endogenous level of total Keratin 18 protein.

Applications Notes

Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100

Symbol

KRT18

NCBI Official Name

Keratin 18

NCBI Organism

Homo sapiens

Background Reference 01

Ramaekers, F. C. and Bosman, F. T. (2004) J. Pathol. 204, 351-354. Chang, L. and Goldman, R. D. (2004) Nat. Rev. Mol. Cell Biol. 5, 601-613. Moll, R. et al. (1982) Cell 31, 11-24.