Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

P62Dok (Ab 398) Antibody

Product Specifications

Background

DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK1 appears to be a negative regulator of the insulin signaling pathway. Modulates integrin activation by competing with talin for the same binding site on ITGB3.

NCBI Gene ID

1796

Swiss Prot

Q99704

Accession Number

NP_001372.1

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

P62Dok (Ab-398) antibody was raised against a peptide sequence around aa.396~400 (P-I-Y-D-E) derived from Human p62Dok.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Concentration

1 mg/mL

Buffer

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store antibody at -20˚ C for up to one year.

Calculated Molecular Weight

62 kDa

Specificity

This antibody detects endogenous level of total p62Dok protein.

Applications Notes

Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200

Symbol

DOK1

NCBI Official Name

Docking protein 1, 62kDa (downstream of tyrosine kinase 1)

NCBI Organism

Homo sapiens

Background Reference 01

Michael J. Wick, et, al. (2001) J. Biol. Chem; 276: 42843 - 42850. Paul D. Simoncic, et, al. (2006) Mol. Cell. Biol; 26: 4149 - 4160. Nadia Dube, et, al. (2004) PNAS; 101: 1834. Adam C. Yopp, et al. (2005) J. Immunol; 175: 2913 - 2924.

Other Product Names

P62DOK, CK2A1, DOK1

Tested Applications

WB, IHC, IF

Protein ID

4503357

Physical Properties

Liquid

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Rat PAI2 (Plasminogen Activator Inhibitor 2) ELISA Kit
ER21534 96 Tests

Rat PAI2 (Plasminogen Activator Inhibitor 2) ELISA Kit

Sign In for Pricing
View Details
CYTH4 Antibody - middle region
ARP77293_P050-25UL 25 µL

CYTH4 Antibody - middle region

Sign In for Pricing
View Details
LZTS1 Conjugated Antibody
MBS9449380-01 0.1 mL (Biotin)

LZTS1 Conjugated Antibody

Sign In for Pricing
View Details
LZTS1 Conjugated Antibody
MBS9449380-02 0.1 mL (AF350)

LZTS1 Conjugated Antibody

Sign In for Pricing
View Details
LZTS1 Conjugated Antibody
MBS9449380-03 0.1 mL (AF405)

LZTS1 Conjugated Antibody

Sign In for Pricing
View Details
LZTS1 Conjugated Antibody
MBS9449380-04 0.1 mL (AF488)

LZTS1 Conjugated Antibody

Sign In for Pricing
View Details