PKCtheta (Ab 695) Antibody

Product Specifications

Background

This is a calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme. Essential for T-cell receptor (TCR) -mediated T-cell activation, but is dispensable during TCR-dependent thymocyte development. Links the TCR signaling complex to the activation of NF-κ -B in mature T lymphocytes. Required for interleukin-2 (IL2) production. PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters.

NCBI Gene ID

5588

Swiss Prot

Q04759

Accession Number

NP_006248.1

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

PKCtheta (Ab-695) antibody was raised against a peptide sequence around aa.693~697 (N-F-S-F-M) derived from Human PKCΘ .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Apoptosis, Cancer

Purification

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Concentration

1 mg/mL

Buffer

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store antibody at -20˚ C for up to one year.

Calculated Molecular Weight

80 kDa

Specificity

This antibody detects endogenous level of total PKCΘ protein.

Applications Notes

Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100

Symbol

PRKCQ

NCBI Official Name

Protein kinase C, theta

NCBI Organism

Homo sapiens

Background Reference 01

Xu ZB, et al. (2004) J Biol Chem 279:50401-50409Thebault S, et al. (2004) Mol Immunol 40: 931-942

Other Product Names

PRKCT, nPKC-theta, MAPTL, MTBT1, TAU, KPCT, PKC-theta, PKCQ, PRKCQ, PRKCT

Tested Applications

WB, IHC

Protein ID

5453976

Physical Properties

Liquid

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

ABC-TC5587 1 Vial

MIA Paca2

Ask

View Details

MBS6146773-01 0.1 mL

DAZ1 (Deleted in Azoospermia Protein 1, DAZ, SPGY) (FITC)

Ask

View Details

MBS6146773-02 5x 0.1 mL

DAZ1 (Deleted in Azoospermia Protein 1, DAZ, SPGY) (FITC)

Ask

View Details

MBS267112-01 48 Well

Porcine beta anti-galactan proteins IgG (beta-AGP IgG) ELISA Kit

Ask

View Details

MBS267112-02 96 Well

Porcine beta anti-galactan proteins IgG (beta-AGP IgG) ELISA Kit

Ask

View Details

MBS267112-03 5x 96 Well

Porcine beta anti-galactan proteins IgG (beta-AGP IgG) ELISA Kit

Ask

View Details