SEK1 / MKK4 (Ab 261) Antibody
Product Specifications
Background
Dual specificity kinase that activates the JUN kinases MAPK8 (JNK1) and MAPK9 (JNK2) as well as MAPK14 (p38) but not MAPK1 (ERK2) or MAPK3 (ERK1) .
NCBI Gene ID
6416
Swiss Prot
P45985
Accession Number
NP_003001.1
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
SEK1/MKK4 (Ab-261) antibody was raised against a peptide sequence around aa.259~263 (A-K-T-R-D) derived from Human SEK1/MKK4.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Concentration
1 mg/mL
Buffer
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store antibody at -20˚ C for up to one year.
Calculated Molecular Weight
44 kDa
Specificity
This antibody detects endogenous level of total SEK1/MKK4 protein.
Applications Notes
Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200
Symbol
MAP2K4
NCBI Official Name
Mitogen-activated protein kinase kinase 4
NCBI Organism
Homo sapiens
Background Reference 01
Wang W, et al. (2002) Mol Cell Biol; 22 (10) : 3389-403. Leung IW, et al. (2001) J Biol Chem; 276 (3) : 1961-7.
Other Product Names
JNKK, MEK4, MKK4, SEK1, SKK1, JNKK1, SERK1, MAPKK4, PRKMK4, SAPKK1, SAPKK-1, C9orf88, JNKK, MAP2K4, MAPK/ERK kinase 4, MAPKK 4
Tested Applications
IHC, IF
Protein ID
4506889
Physical Properties
Liquid
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