EGFR (Ab 1092) Antibody

Product Specifications

Background

Receptor for EGF, but also for other members of the EGF family, as TGF-alpha, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. Is involved in the control of cell growth and differentia

NCBI Gene ID

1956

Swiss Prot

P00533

Accession Number

NP_005219.2

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

EGFR (Ab-1092) antibody was raised against a peptide sequence around aa. 1090~1094 (P-E-Y-I-N) derived from Human EGFR.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Concentration

1 mg/mL

Buffer

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store antibody at -20˚ C for up to one year.

Calculated Molecular Weight

175 kDa

Specificity

This antibody detects endogenous level of total EGFR protein.

Applications Notes

Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100

Symbol

EGFR

NCBI Official Name

Epidermal growth factor receptor

NCBI Organism

Homo sapiens

Background Reference 01

Buerger C, et al. (2003) J Biol Chem; 278 (39) : 37610-21. Wang XQ, (2003) J Biol Chem; 278 (49) : 48770-8. Saito T, et al. (2004) Endocrinology; 145 (9) : 4232-43. Pao W, et al. (2004) Proc Natl Acad Sci U S A; 101 (36) : 13306-11. Mattila E, et al. (2005) Nat Cell Biol; 7 (1) : 78-85.