Elk 1 (Ab 383) Antibody
Product Specifications
Background
Elk-1 is a member of the Ets family of transcription factors and of the ternary complex factor (TCF) subfamily. Proteins of the TCF subfamily form a ternary complex by binding to the the serum response factor and the serum reponse element in the promoter of the c-fos proto-oncogene. The protein encoded by this gene is a nuclear target for the ras-raf-MAPK signaling cascade. Alternatively spliced transcript variants encoding the same protein have been found for this gene
NCBI Gene ID
2002
Swiss Prot
P19419
Accession Number
NP_001107595.1
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Elk-1 (Ab-383) antibody was raised against a peptide sequence around aa.381~385 (T-L-S-P-I) derived from Human Elk1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Concentration
1 mg/mL
Buffer
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store antibody at -20˚ C for up to one year.
Calculated Molecular Weight
47 kDa
Specificity
This antibody detects endogenous level of total Elk-1 protein.
Applications Notes
Immunohistochemistry: 1:50~1:100
Symbol
ELK1
NCBI Official Name
ELK1, member of ETS oncogene family
NCBI Organism
Homo sapiens
Background Reference 01
Xing J, et al. (1996) Science. 273 (5277) : 959-963. Janknecht R, et al. (1993) EMBO J. 12 (13) : 5097-5104. Marais R, et al. (1993) Cell 73: 381-393. Kortenjann M, et al. (1994) Mol Cell Biol. 14: 4815-4824. Cavigelli M, et al. (1995) EMBO J. 14: 5957-5964. Whitmarsh A J, et al. (1995) Science. 269:403-407.
Other Product Names
Mek5, Mkk5, Prkmk5, ELK1, ETS-domain protein Elk-1
Tested Applications
IHC
Protein ID
166362732
Physical Properties
Liquid
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