Her3 / ErbB3 (phospho Tyr1328) Antibody

Product Specifications

Background

Binds and is activated by neuregulins and NTAK.

NCBI Gene ID

2065

Swiss Prot

P21860

Accession Number

NP_001005915.1

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Her3/ErbB3 (phospho-Tyr1328) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 1328 (P-D-Y (p) -W-H) derived from Human Her3/ErbB3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Phospho-Specific

Purification

Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

Concentration

1 mg/mL

Buffer

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Modification

Phospho-Specific

Shipping Conditions

Blue Ice

Storage Conditions

Store antibody at -20˚ C for up to one year.

Calculated Molecular Weight

185 kDa

Specificity

This antibody detects endogenous level of Her3/ErbB3 only when phosphorylated at tyrosine 1328.

Applications Notes

Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200

Symbol

ERBB3

NCBI Official Name

V-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3

NCBI Organism

Homo sapiens

Background Reference 01

Holbro, T. et al. (2003) Proc. Natl. Acad. Sci. USA 100, 8933-8938. Kobayashi, M. et al. (2003) Oncogene 22, 1294-1301. Kim, H. H. et al. (1994) J. Biol. Chem. 269, 24747-24755. Yarden, Y. and Sliwkowski, M. X. (2001) Nature Rev. Mol. Cell. Biol. 2, 127-137.

Other Product Names

HER3, LCCS2, ErbB-3, c-erbB3, erbB3-S, MDA-BF-1, c-erbB-3, p180-ErbB3, p45-sErbB3, p85-sErbB3, KIAA0288, Tyrosine kinase-type cell surface receptor HER3