Stathmin 1 (phospho Ser25) Antibody

Product Specifications

Background

Involved in the regulation of the microtubule (MT) filament system by destabilizing microtubules. Prevents assembly and promotes disassembly of microtubules. Phosphorylation at Ser-16 may be required for axon formation during neurogenesis. Involved in the control of the learned and innate fear

NCBI Gene ID

3925

Swiss Prot

P16949

Accession Number

NP_001138926.1

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Stathmin 1 (Phospho-Ser25) antibody was raised against a peptide sequence around phosphorylation site of serine 25 (I-L-S (p) -P-R) derived from Human Stathmin 1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Phospho-Specific

Purification

Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

Concentration

1 mg/mL

Buffer

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Modification

Phospho-Specific

Shipping Conditions

Blue Ice

Storage Conditions

Store antibody at -20˚ C for up to one year.

Calculated Molecular Weight

19 kDa

Specificity

This antibody detects endogenous level of Stathmin 1 only when phosphorylated at serine 25.

Applications Notes

Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100

Symbol

STMN1

NCBI Official Name

Stathmin 1

NCBI Organism

Homo sapiens

Background Reference 01

Boehm M, et al. (2002) EMBO J 21 (13) : 3390-3401. Vadlamudi RK, et al. (2005) Mol Cell Biol 25 (9) : 3726-3736. Zilfou JT, et al. (2001) Mol Cell Biol 21 (12) : 3974-3985. Biernat J, et al. (2002) Mol Biol Cell 13 (11) : 4013-4028.