HDAC2 (phospho Ser394) Antibody
Product Specifications
Background
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4) . Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes
NCBI Gene ID
3066
Swiss Prot
Q92769
Accession Number
NP_001518.2
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
HDAC2 (Phospho-Ser394) antibody was raised against a peptide sequence around phosphorylation site of serine 394 (E-D-S (p) -G-D) derived from Human HDAC2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Phospho-Specific, Cell Cycle
Purification
Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Concentration
1 mg/mL
Buffer
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Modification
Phospho-Specific
Shipping Conditions
Blue Ice
Storage Conditions
Store antibody at -20˚ C for up to one year.
Calculated Molecular Weight
60 kDa
Specificity
This antibody detects endogenous level of HDAC2 only when phosphorylated at serine 394.
Applications Notes
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200
Symbol
HDAC2
NCBI Official Name
Histone deacetylase 2
NCBI Organism
Homo sapiens
Background Reference 01
Tsai SC, et al. (2002) J Biol Chem; 277 (35) : 31826-33
Other Product Names
HD2, RPD3, YAF1, PRKCT, HD2
Tested Applications
WB, IHC, IF
Protein ID
116284376
Physical Properties
Liquid
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