Estrogen Receptor a (phospho Ser118) Antibody
Product Specifications
Background
Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.
NCBI Gene ID
2099
Swiss Prot
P03372
Accession Number
NP_000116.2
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Estrogen Receptor-a (Phospho-Ser118) antibody was raised against a peptide sequence around phosphorylation site of serine 118 (Q-L-S (p) -P-F) derived from Human Estrogen Receptor-α .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Phospho-Specific
Purification
Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Concentration
1 mg/mL
Buffer
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Modification
Phospho-Specific
Shipping Conditions
Blue Ice
Storage Conditions
Store antibody at -20˚ C for up to one year.
Calculated Molecular Weight
66 kDa
Specificity
This antibody detects endogenous level of Estrogen Receptor-α only when phosphorylated at serine 118.
Applications Notes
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200
Symbol
ESR1
NCBI Official Name
Estrogen receptor 1
NCBI Organism
Homo sapiens
Background Reference 01
Ramsauer VP, et al. (2003) J Biol Chem; 278 (32) : 30142-7. Jepson S, et al. (2002) Oncogene; 21 (49) : 7524-32. Ren Z, et al. (2002) J Biol Chem; 277 (41) : 38486-93. Eppenberger-Castori S, et al. (2001) J Clin Oncol; 19 (3) : 645-56.
Other Product Names
ER, ESR, Era, ESRA, ESTRR, NR3A1, BBC6, BCL2L8, ER, ESR1, ESTR, ESTRA
Tested Applications
WB, IHC, IF
Protein ID
62821794
Physical Properties
Liquid
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