STAT6 (phospho Tyr641) Antibody

Product Specifications

Background

Carries out a dual function: signal transduction and activation of transcription. Involved in interleukin-4 signalling.

NCBI Gene ID

6778

Swiss Prot

P42226

Accession Number

NP_003144.3

Host

Rabbit

Reactivity

Human

Immunogen

STAT6 (Phospho-Tyr641) antibody was raised against a peptide sequence around phosphorylation site of Tyrosine 641 (R-G-Y (p) -V-P) derived from Human STAT6.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Phospho-Specific

Purification

Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

Concentration

1 mg/mL

Buffer

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Modification

Phospho-Specific

Shipping Conditions

Blue Ice

Storage Conditions

Store antibody at -20˚ C for up to one year.

Calculated Molecular Weight

110 kDa

Specificity

This antibody detects endogenous level of STAT6 only when phosphorylated at tyrosine 641.

Applications Notes

Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100

Symbol

STAT6

NCBI Official Name

Signal transducer and activator of transcription 6, interleukin-4 induced

NCBI Organism

Homo sapiens

Background Reference 01

Nelms K, et al. (1999) Annu Rev Immunol. 17:701-738. Malabarba M G, et al. (1996) Biochem. J. 319:865-872. Hou J, et al. (1994) Science. 265:1701-1706. Quelle F W, et al. (1995) Mol Cell Biol. 15: 3336-3343. Takeda K, et al. (1996) Nature. 380: 627-630.