STAT5A (phospho Ser780) Antibody

Product Specifications

Background

Carries out a dual function: signal transduction and activation of transcription. Binds to the GAS element and activates PRL-induced transcription.

NCBI Gene ID

6776

Swiss Prot

P42229

Accession Number

NP_003143.2

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

STAT5A (Phospho-Ser780) antibody was raised against a peptide sequence around phosphorylation site of serine 780 (R-L-S (p) -P-P) derived from Human STAT5A.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Phospho-Specific

Purification

Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

Concentration

1 mg/mL

Buffer

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Modification

Phospho-Specific

Shipping Conditions

Blue Ice

Storage Conditions

Store antibody at -20˚ C for up to one year.

Calculated Molecular Weight

90 kDa

Specificity

This antibody detects endogenous level of STAT5A only when phosphorylated at serine 780.

Applications Notes

Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100

Symbol

STAT5A

NCBI Official Name

Signal transducer and activator of transcription 5A

NCBI Organism

Homo sapiens

Background Reference 01

Gouilleux F, et al. (1994) EMBO J. 13: 4361-4369. Dentelli P, et al. (1999) J Immunol. 163: 2151-2159. Meinke A, et al. (1996) Mol Cell Biol. 16: 6937-6944.