VEGF-R2 Antibody

Product Specifications

Background

Vascular endothelial growth factor receptor 2; Protein-tyrosine kinase receptor Flk-1; kinase insert domain receptor. Receptor for VEGF or VEGF-C. It has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. It belongs to the csf-1/pdgf receptor family of tyrosine-protein kinases.

NCBI Gene ID

3791

Swiss Prot

P35968

Accession Number

P35968

Host

Chicken

Reactivity

Human, Mouse, Rat

Immunogen

51-119

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Growth Factors, Signal Transduction

Purification

Antigen affinity-purified

Concentration

1 mg/mL

Buffer

Phosphate-Buffered Saline. No preservatives added.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

VEGF-R2 antibody can be stored at 4˚ C for short term (weeks) . Long term storage should be at -20˚ C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

151.5 kDa (calculated)

Applications Notes

VEGF-R2 antibody can be used for the detection of VEGF-R2 by Western blot, IHC, may also work for ICC.

Symbol

KDR

NCBI Official Name

Kinase insert domain receptor (a type III receptor tyrosine kinase)

NCBI Organism

Homo sapiens

Background Reference 01

Kiba, A., Yabana, N. and Shibuya, M. A set of loop-1 and -3 structures in the novel vascular endothelial growth factor (VEGF) family member, VEGF-ENZ-7, is essential for the activation of VEGFR-2 signaling. J. Biol. Chem. 278 (15), 13453-13461 (2003) .