JUN Antibody
Product Specifications
Background
V-jun avian sarcoma virus 17 oncogene homolog; Jun activation domain binding protein. The human protooncogene JUN is the putative transforming gene of avian sarcoma virus 17, and it encodes a protein which is highly homologous to the viral protein. The JUN gene product has also been shown to be structurally and functionally identical to the enhancer binding protein, AP-1; thus AP-1 may be encoded by JUN. The JUN protein interacts directly with specific target DNA sequences to regulate gene expression. JUN has been mapped to 1p32-p31, a chromosomal region involved in both translocations and deletions in human malignancies.
NCBI Gene ID
3725
Swiss Prot
P05412
Accession Number
NP_002219.1
Host
Chicken
Reactivity
Human, Mouse, Rat
Immunogen
1-240
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction, Inflammasomes
Purification
Antigen affinity-purified
Concentration
1 mg/mL
Buffer
Phosphate-Buffered Saline. No preservatives added.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
JUN antibody can be stored at 4˚ C for short term (weeks) . Long term storage should be at -20˚ C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=XW-7318
Calculated Molecular Weight
35.7 kDa (calculated)
Applications Notes
Jun antibody can be used for the detection of Jun by Western blot, may also work for IHC and ICC.
Symbol
JUN
NCBI Official Name
Jun proto-oncogene
NCBI Organism
Homo sapiens
Background Reference 01
Eferl, R., Ricci, R., Kenner, L., Zenz, R., David, J. -P., Rath, M., Wagner, E. F. Liver tumor development: c-Jun antagonizes the proapoptotic activity of p53. Cell 112: 181-192, 2003.
Other Product Names
Transcription factor AP-1, Activator protein 1, AP1, AP-1, c-Jun, Jun
Tested Applications
WB
Protein ID
4758616, 386839
Physical Properties
Liquid
Curated Selection
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