GNAI3 Antibody

Product Specifications

Background

GNα i3, Guanine nucleotide binding protein (G protein), α inhibiting activity polypeptide 3. Gα i3 is the a subunit of inhibitory trimeric G protein (Gi), which inhibits adenylate cyclase following its G-protein coupled receptors (GPCR) such as a2-adrenergic receptors are activated. Gα i3 can be inactivated by pertussis toxin.

NCBI Gene ID

2773

Swiss Prot

P08754

Accession Number

NP_006487.1

Host

Chicken

Reactivity

Human, Mouse, Rat

Immunogen

C-terminal peptide (KNNLKECGLY)

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction, Autophagy

Purification

Antigen affinity-purified

Concentration

1 mg/mL

Buffer

Phosphate-Buffered Saline. No preservatives added.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

GNAI3 antibody can be stored at 4˚ C for short term (weeks) . Long term storage should be at -20˚ C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

40.4 kDa (calculated)

Applications Notes

Gai3 antibody can be used for the detection of Gai3 by ICC, may also work for IHC and Wetern blot.

Symbol

GNAI3

NCBI Official Name

Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3

NCBI Organism

Homo sapiens

Background Reference 01

Miotti, S., Bagnoli, M., Tomassetti, A., Colnaghi, M. I. and Canevari, S. Interaction of folate receptor with signaling molecules lyn and G (alpha) (i-3) in detergent-resistant complexes from the ovary carcinoma cell line IGROV1 J. Cell. Sci. 113 Pt 2, 349-357 (2000) .