CRH Antibody

Product Specifications

Background

Corticotropin releasing hormone precursor. CRH is a 41-amino acid peptide derived from a 191-amino acid preprohormone. CRH is secreted by the paraventricular nucleus (PVN) of the hypothalamus in response to stress. It is also synthesized in peripheral tissues, such as T lymphocytes and is highly expressed in the placenta. In the placenta CRH is a marker that determines the length of gestation and the timing of parturition and delivery.

NCBI Gene ID

1392

Swiss Prot

P06850

Accession Number

NP_000747.1

Host

Chicken

Reactivity

Human, Mouse, Rat

Immunogen

27-196

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

Antigen affinity-purified

Concentration

1 mg/mL

Buffer

Phosphate-Buffered Saline. No preservatives added.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

CRH antibody can be stored at 4˚ C for short term (weeks) . Long term storage should be at -20˚ C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

21.4 kDa (calculated)

Applications Notes

CRH antibody can be used for the detection of CRH by Western blot, may also work for IHC and ICC.

Symbol

CRH

NCBI Official Name

Corticotropin releasing hormone

NCBI Organism

Homo sapiens

Background Reference 01

Shibahara, S., Morimoto, Y., Furutani, Y., Notake, M., Takahashi, H., Shimizu, S., Horikawa, S., Numa, S. Isolation and sequence analysis of the human corticotropin-releasing factor precursor gene. EMBO J. 2: 775-779, 1983.