MYC Antibody

Product Specifications

Background

C-myc, v-myc myelocytomatosis viral oncogene homolog. This protein participates in the regulation of gene transcription. It binds DNA both in a non-specific manner and also specifically to recognizes the core sequence CAC[GA]TG. Seems to activate the transcription of growth-related genes.

NCBI Gene ID

4609

Swiss Prot

P01106

Accession Number

NP_002458.1

Host

Chicken

Reactivity

Human, Mouse, Rat

Immunogen

268-386

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

Antigen affinity-purified

Concentration

1 mg/mL

Buffer

Phosphate-Buffered Saline. No preservatives added.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

MYC antibody can be stored at 4˚ C for short term (weeks) . Long term storage should be at -20˚ C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

48.8 kDa (calculated)

Applications Notes

C-myc (N-88) antibody can be used for the detection of C-myc (N-88) by Western blot, may also work for IHC and ICC.

Symbol

MYC

NCBI Official Name

V-myc avian myelocytomatosis viral oncogene homolog

NCBI Organism

Homo sapiens

Background Reference 01

Adams, J. M., Gerondakis, S., Webb, E., Corcoran, L. M., Cory, S. Cellular myc oncogene is altered by chromosome translocation to an immunoglobulin locus in murine plasmacytomas and is rearranged similarly in human Burkitt lymphomas. Proc. Nat. Acad. Sci. 80: 1982-1986, 1983.