C1QA Antibody
Product Specifications
Background
C1q. C1q associates with the proenzymes C1R and C1S to yield C1, the first component of the serum complement system. Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N terminus and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on chromosome 1.
NCBI Gene ID
712
Swiss Prot
P02745
Accession Number
NP_057075.1 (A), NP_000482.2 (B), NP_758957.1 (C)
Host
Chicken
Reactivity
Human
Immunogen
Human plasma C1q protein
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction, Innate Immunity, Neuroscience
Purification
Antigen affinity-purified
Concentration
1 mg/mL
Buffer
Phosphate-Buffered Saline. No preservatives added.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
C1QA antibody can be stored at 4˚ C for short term (weeks) . Long term storage should be at -20˚ C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
26 kDa (calculated)
Applications Notes
C1q antibody can be used for the detection of C1q by Western blot, ELISA, may also work for IHC and ICC.
Symbol
C1QA
NCBI Official Name
Complement component 1, q subcomponent, A chain
NCBI Organism
Homo sapiens
Background Reference 01
Leigh, L. E. et al. C1q-mediated chemotaxis by human neutrophils: involvement of gClqR and G-protein signaling mechanisms Biochem. J. 330 (Pt 1), 247-254 (1998) .
Other Product Names
Complement C1q subcomponent subunit A
Tested Applications
ELISA
Protein ID
7705753 (A), 11038662 (B), 27363488 (C)
Physical Properties
Liquid
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