ATP7A Antibody

Product Specifications

Background

ATPase, Copper-transporting, α polypeptide; Copper-transporting ATPase 1. Copper-transporting ATPase 1 is an integral membrane protein cycling constitutively between the trans-golgi network and the plasma membrane. It may supply copper to copper-requiring proteins within the secretory pathway, when localized in the trans-golgi network. Under conditions of elevated extracellular copper, it relocalized to the plasma membrane where it functions in the efflux of copper from cells.

NCBI Gene ID

538

Swiss Prot

Q04656

Accession Number

NP_000043.1

Host

Chicken

Reactivity

Human, Mouse, Rat

Immunogen

1407-1500

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Innate Immunity, Signal Transduction

Purification

Antigen affinity-purified

Concentration

1 mg/mL

Buffer

Phosphate-Buffered Saline. No preservatives added.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

ATP7A antibody can be stored at 4˚ C for short term (weeks) . Long term storage should be at -20˚ C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

163.3 kDa (calculated)

Applications Notes

ATP7A antibody can be used for the detection of ATP7A by Western blot, may also work for IHC and ICC.

Symbol

ATP7A

NCBI Official Name

ATPase, Cu++ transporting, alpha polypeptide

NCBI Organism

Homo sapiens

Background Reference 01

Vulpe, C., Levinson, B., Whitney, S., Packman, S. and Gitschier, J. Isolation of a candidate gene for Menkes disease and evidence that it encodes a copper-transporting ATPase Nat. Genet. 3 (1), 7-13 (1993) .