AKT2 Antibody

Product Specifications

Background

Murine thymoma viral (v-akt) homolog-2; rac protein kinase β . AKT2 is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. Furthermore, AKT2 was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression of AKT2 contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. AKT2 is a general protein kinase capable of phophorylating several known proteins.

NCBI Gene ID

208

Swiss Prot

P31751

Accession Number

NP_001617.1

Host

Chicken

Reactivity

Human

Immunogen

108-124

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Apoptosis, Neuroscience, Signal Transduction

Purification

Antigen affinity-purified

Concentration

1 mg/mL

Buffer

Phosphate-Buffered Saline. No preservatives added.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

AKT2 antibody can be stored at 4˚ C for short term (weeks) . Long term storage should be at -20˚ C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

55.8 kDa (calculated)

Applications Notes

AKT2 antibody can be used for the detection of AKT2 by Western blot, ELISA, may also work for IHC and ICC.

Symbol

AKT2

NCBI Official Name

V-akt murine thymoma viral oncogene homolog 2

NCBI Organism

Homo sapiens

Background Reference 01

Cheng, J. Q., Ruggeri, B., Klein, W. M., Sonoda, G., Altomare, D. A., Watson, D. K., Testa, J. R. Amplification of AKT2 in human pancreatic cancer cells and inhibition of AKT2 expression and tumorigenicity by antisense RNA. Proc. Nat. Acad. Sci. 93: 3636-3641, 1996.