TGFbeta1 Antibody [4F9C10]
Product Specifications
Background
TGF beta (transforming growth factor beta), with 390-amino acid protein (about 43 kDa), is a multifunctional peptide that controls proliferation, differentiation, and other functions in many cell types. In mammals, three isoforms of TGFbeta, that is, beta1, beta2, and beta3, are known. TGF beta is one of numerous inhibitory factors produced by cancer cells that regulate antitumor immunity. TGF beta1 takes part in the local response in the course of primary lung cancer and TGFbeta1 is thought to be implicated in breast cancer progression.TGFbeta1 also plays a critical role in the downregulation of microglial responses minimizing brain inflammation and thus avoiding exacerbation of brain damage.
NCBI Gene ID
7040
Swiss Prot
P01137
Accession Number
P01137
Host
Mouse
Reactivity
Human
Immunogen
Ni-NTA purified truncated recombinant TGFbeta1 expressed in E. Coli strain BL21 (DE3) .
Clonality
Monoclonal
Clone
4F9C10
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Growth Factors, Growth Factors
Concentration
Batch dependent
Buffer
Ascitic fluid containing 0.03% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
TGF beta1 monoclonal antibody can be stored at -20˚ C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=32-224
Fragment
IgG2a
Symbol
TGFB1
NCBI Official Name
Transforming growth factor, beta 1
NCBI Organism
Homo sapiens
Background Reference 01
Delphine Boche, Colm Cunningham, Fabian Docagne. Neurobiol Dis. 2006 Feb 27
Background Reference 02
Shizuya Saika. Lab Invest. 2006 Feb;86 (2) :106-15
Other Product Names
TGFBTGF-beta-1, CED, LAP, DPD1, TGFB, TGFbeta
Tested Applications
ELISA, WB
Protein ID
135674
Curated Selection
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