SNCG Antibody [1H10D2]
Product Specifications
Background
SNCG (also designated gamma-synuclein or breast cancer-specific protein 1), with 127-amino acid protein (about 14 kDa), belongs to the synuclein family, which also includes alpha- and beta- synuclein.Three synucleins are located in the neuronal cytosol and enriched in presynaptic terminals, while SNCG is also expressed in many other non-neuronal tissues. SNCG is abnormally expressed in a high percentage of tumor tissues of diversified cancer types, including liver, esophagus, colon, gastric, lung, prostate, cervical, and breast cancer, but rarely expressed in tumor-matched nonneoplastic adjacent tissues. High levels of SNCG have been identified in advanced breast carcinomas suggesting a correlation between overexpression of SNCG and breast tumor development.
NCBI Gene ID
6623
Swiss Prot
O76070
Accession Number
O76070
Host
Mouse
Reactivity
Human
Immunogen
Ni-NTA purified truncated recombinant SNCG expressed in E. Coli strain BL21 (DE3) .
Clonality
Monoclonal
Clone
1H10D2
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Antibody is purified by protein A affinity chromatography.
Concentration
Batch dependent
Buffer
Ascitic fluid containing 0.03% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
SNCG (breast cancer-specific protein 1) monoclonal antibody can be stored at -20˚ C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=32-216
Fragment
IgG1
Symbol
SNCG
NCBI Official Name
Synuclein, gamma (breast cancer-specific protein 1)
NCBI Organism
Homo sapiens
Background Reference 01
Haiyan Liu, Wei Liu, Yinwei Wu. Cancer Res. 2005 Sep 1;65 (17) :7635-43.
Background Reference 02
Rina Surgucheva , Belinda McMahon , Andrei Surguchov. Cell Motil Cytoskeleton. 2006 May 26.
Other Product Names
BCSG1, PERSYN, PRSN, Breast cancer-specific gene 1 protein, SR, BCSG1
Tested Applications
ELISA, WB, IHC
Protein ID
90110074
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
