SNCG Antibody [1H10D2]
Product Specifications
Background
SNCG (also designated gamma-synuclein or breast cancer-specific protein 1), with 127-amino acid protein (about 14 kDa), belongs to the synuclein family, which also includes alpha- and beta- synuclein.Three synucleins are located in the neuronal cytosol and enriched in presynaptic terminals, while SNCG is also expressed in many other non-neuronal tissues. SNCG is abnormally expressed in a high percentage of tumor tissues of diversified cancer types, including liver, esophagus, colon, gastric, lung, prostate, cervical, and breast cancer, but rarely expressed in tumor-matched nonneoplastic adjacent tissues. High levels of SNCG have been identified in advanced breast carcinomas suggesting a correlation between overexpression of SNCG and breast tumor development.
NCBI Gene ID
6623
Swiss Prot
O76070
Accession Number
O76070
Host
Mouse
Reactivity
Human
Immunogen
Ni-NTA purified truncated recombinant SNCG expressed in E. Coli strain BL21 (DE3) .
Clonality
Monoclonal
Clone
1H10D2
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Antibody is purified by protein A affinity chromatography.
Concentration
Batch dependent
Buffer
Ascitic fluid containing 0.03% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
SNCG (breast cancer-specific protein 1) monoclonal antibody can be stored at -20˚ C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Fragment
IgG1
Symbol
SNCG
NCBI Official Name
Synuclein, gamma (breast cancer-specific protein 1)
NCBI Organism
Homo sapiens
Background Reference 01
Haiyan Liu, Wei Liu, Yinwei Wu. Cancer Res. 2005 Sep 1;65 (17) :7635-43.
Background Reference 02
Rina Surgucheva , Belinda McMahon , Andrei Surguchov. Cell Motil Cytoskeleton. 2006 May 26.
Other Product Names
BCSG1, PERSYN, PRSN, Breast cancer-specific gene 1 protein, SR, BCSG1
Tested Applications
ELISA, WB, IHC
Protein ID
90110074
Frequently Asked Questions
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