S100A Antibody [2C8B8 / 2C8E8]

Product Specifications

Background

S100 calcium binding protein A1 (S100-alpha/ S100A1), The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-induced Ca2+ release, inhibition of microtubule assembly, and inhibition of protein kinase C-mediated phosphorylation. Reduced expression of this protein has been implicated in cardiomyopathies.

NCBI Gene ID

6271

Swiss Prot

P23297

Accession Number

P23297

Host

Mouse

Reactivity

Human

Immunogen

Ni-NTA purified truncated recombinant S100A expressed in E. Coli strain BL21 (DE3) .

Clonality

Monoclonal

Clone

2C8B8 / 2C8E8

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

Antibody is purified by protein A affinity chromatography.

Concentration

Batch dependent

Buffer

Ascitic fluid containing 0.03% sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

S100A monoclonal antibody can be stored at -20˚ C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.