TUG Antibody [4A11A6G11]

Product Specifications

Background

The TUG protein contains a UBX domain, for GLUT4. In truncated form, TUG acts in a dominant-negative manner to inhibit insulin-stimulated GLUT4 redistribution in Chinese hamster ovary cells and 3T3-L1 adipocytes. Full-length TUG forms a complex specifically with GLUT4. In 3T3-L1 adipocytes, this complex is present in unstimulated cells and is largely disassembled by insulin. Endogenous TUG is localized with the insulin-mobilizable pool of GLUT4 in unstimulated 3T3-L1 adipocytes, and is not mobilized to the plasma membrane by insulin.

NCBI Gene ID

79058

Swiss Prot

Q9BZE9

Accession Number

Q9BZE9

Host

Mouse

Reactivity

Mouse

Immunogen

Ni-NTA purified truncated recombinant TUG expressed in E. Coli strain BL21 (DE3) .

Clonality

Monoclonal

Clone

4A11A6G11

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Growth Factors

Purification

Antibody is purified by protein A affinity chromatography and resuspended in PBS with 0.2%BSA, 0.09% sodium azide.

Concentration

Batch dependent

Buffer

Purified antibody in PBS containing 0.03% sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Mouse TUG monoclonal antibody can be stored at -20˚ C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.