MAPK11 Antibody [4H6H6]

Product Specifications

Background

Mitogen-activated protein kinase 11.The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. This kinase is most closely related to p38 MAP kinase, both of which can be activated by proinflammatory cytokines and environmental stress. This kinase is activated through its phosphorylation by MAP kinase kinases (MKKs), preferably by MKK6. Transcription factor ATF2/CREB2 has been shown to be a substrate of this kinase.

NCBI Gene ID

5600

Swiss Prot

Q15759

Accession Number

NP_002742.3

Host

Mouse

Reactivity

Human

Immunogen

Purified truncated recombinant MAPK11 (aa251-363) -Trx fusion protein is expressed in E. Coli strain BL21 (DE3) .

Clonality

Monoclonal

Clone

4H6H6

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Concentration

Batch dependent

Buffer

Ascitic fluid containing 0.03% sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

MAPK11 monoclonal antibody can be stored at -20˚ C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.