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LSD1AOF2 Antibody [1B2F2 / 1B2E5]

Product Specifications

Background

The amine oxidase domain 2 (AOF2) gene encodes a nuclear protein (LSD1, ~95 kDa) containing a Swirm domain, a FAD-binding motif, and an amine oxidase domain. This protein is a component of several histone deacetylase complexes, though it silences genes by functioning as a histone demethylase. LSD1 is a chromatin-modifying enzyme, which serve as a docking module for the stabilization of the associated corepressor complex (es) on chromatin.

NCBI Gene ID

23028

Swiss Prot

O60341

Accession Number

O60341

Host

Mouse

Reactivity

Human

Immunogen

Ni-NTA purified truncated recombinant human LSD1 expressed in E. Coli strain BL21 (DE3) .

Clonality

Monoclonal

Clone

1B2F2 / 1B2E5

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Concentration

Batch dependent

Buffer

Ascitic fluid containing 0.03% sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

LSD1/AOF2 monoclonal antibody can be stored at -20˚ C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Fragment

IgG1

Symbol

KDM1A

NCBI Official Name

Lysine (K) -specific demethylase 1A

NCBI Organism

Homo sapiens

Background Reference 01

Shi YJ, et.al Mol Cell. 2005 Sep 16;19 (6) :857-64.

Background Reference 02

Metzger E, et.al Nature. 2005 Sep 15;437 (7057) :436-9.

Other Product Names

AOF2, KDM1, KIAA0601, LSD1, BRAF35-HDAC complex protein BHC110AOF2, BHC110

Tested Applications

ELISA, WB, IHC

Protein ID

51315808

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