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IL-8 Antibody [3E4D8]

Product Specifications

Background

Interleukin-8 (IL-8) is a member of the CXC chemokine family. This chemokine is one of the major mediators of the inflammatory response. This chemokine is secreted by several cell types. It functions as a chemoattractant, and is also a potent angiogenic factor. IL-8 is believed to play a role in the pathogenesis of bronchiolitis, a common respiratory tract disease caused by viral infection. IL-8 and other ten members of the CXC chemokine gene family form a chemokine gene cluster in a region mapped to chromosome 4q.

NCBI Gene ID

3576

Swiss Prot

P10145

Accession Number

P10145

Host

Mouse

Reactivity

Human

Immunogen

Ni-NTA purified recombinant human IL-8 expressed in E.Coli. strain BL21 (DE3) .

Clonality

Monoclonal

Clone

3E4D8

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology

Purification

Antibody is purified by protein A affinity chromatography.

Concentration

Batch dependent

Buffer

Purified antibody in PBS containing 0.03% sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

IL-8 monoclonal antibody can be stored at -20˚ C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Fragment

IgG1.kappa

Symbol

IL8

NCBI Official Name

Interleukin 8

NCBI Organism

Homo sapiens

Background Reference 01

Baggiolini M. et al. 1991. FEBS Lett. 307:97-101.

Background Reference 02

Mukaida N. et al. 1989. J.Immunol.143:1366-1371.

Other Product Names

CXCL8, C-X-C motif chemokine 8, IL-8, NAF, GCP1, LECT, LUCT, NAP1, CXCL8, GCP-1, LYNAP, MDNCF, MONAP, NAP-1

Tested Applications

ELISA, WB

Protein ID

124359

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