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IgG Antibody [4D2D9G8]

Product Specifications

Background

Monoclonal anti-human IgG is derived from the hybridoma1 produced by the fusion of mouse myeloma cells and splenocytes from an immunized mouse. It is specific for the whole human IgG molecule, has no across action with human IgM molecule as determined by an ELISA. Reactivity is observed with all human IgG subclasses but not with the Fab fragment of human IgG, the antibody site is located in the terminal end of human IgG (part of the Fab fragment), the Fc portion has various important functions such as complement fixation, site for rheumatoid factor.

NCBI Gene ID

2212

Swiss Prot

P12318

Accession Number

P12318

Host

Mouse

Reactivity

Human

Immunogen

Chrompure Human IgG, Fc Fragment.

Clonality

Monoclonal

Clone

4D2D9G8

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology

Purification

Antibody is purified by protein A affinity chromatography.

Concentration

Batch dependent

Buffer

Purified antibody in PBS containing 0.03% sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

IgG monoclonal antibody can be stored at -20˚ C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Fragment

IgG1

Symbol

FCGR2A

NCBI Official Name

Fc fragment of IgG, low affinity IIa, receptor (CD32)

NCBI Organism

Homo sapiens

Background Reference 01

Roitt, I, et al "Immunology", Mosby, London, England, (1996) fourth edition.

Background Reference 02

Vlug, A. et al "The structure and function of human IgG subclasses". Eur.Clin.Lab. 8, 26 (1989) .

Other Product Names

CD32, FCG2, FCGR2A1, IGFR2, Low affinity immunoglobulin gamma Fc region receptor II-a, CDw32, IgG Fc receptor II-a, FcGR, CD32A, FCGR2

Tested Applications

ELISA, WB

Protein ID

160332371

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