CKit Antibody [8D7B4 / 8D7D4 / 7H6B2 / 7H6B12]
Product Specifications
Background
C-kit (CD117,145 kDa) functions as a tyrosine kinase receptor which becomes activated upon binding of its ligand SCF (stem-cell factor), the C-kit gene encodes the human homolog of the proto-oncogene c-kit. which was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. KIT is a type 3 transmembrane receptor for MGF (mast cell growth factor) . Mutations in KIT are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism.
NCBI Gene ID
3815
Swiss Prot
P10721
Accession Number
P10721
Host
Mouse
Reactivity
Human
Immunogen
Ni-NTA purified truncated recombinant C-kit expressed in E. Coli strain BL21 (DE3) .
Clonality
Monoclonal
Clone
8D7B4 / 8D7D4 / 7H6B2 / 7H6B12
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Innate Immunity
Purification
Antibody is purified by protein A affinity chromatography.
Concentration
Batch dependent
Buffer
Ascitic fluid containing 0.03% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
C-Kit monoclonal antibody can be stored at -20˚ C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Fragment
IgG1
Symbol
KIT
NCBI Official Name
V-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
NCBI Organism
Homo sapiens
Background Reference 01
Mojica WD et.alHistopathology. 2005 Nov;47 (5) :517-22.
Background Reference 02
Tong WD et.alInt J Colorectal Dis. 2005 Jul;20 (4) :363-7. Epub 2005 Feb 2.
Background Reference 03
Nakai Y et.alBiochem Biophys Res Commun. 2005 Nov 11;337 (1) :289-96.
Other Product Names
SCFR, Piebald trait protein, SCFR, PBT, C-Kit, CD117
Tested Applications
ELISA
Protein ID
125472
Frequently Asked Questions
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