CKit Antibody [8D7B4 / 8D7D4 / 7H6B2 / 7H6B12]

Product Specifications

Background

C-kit (CD117,145 kDa) functions as a tyrosine kinase receptor which becomes activated upon binding of its ligand SCF (stem-cell factor), the C-kit gene encodes the human homolog of the proto-oncogene c-kit. which was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. KIT is a type 3 transmembrane receptor for MGF (mast cell growth factor) . Mutations in KIT are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism.

NCBI Gene ID

3815

Swiss Prot

P10721

Accession Number

P10721

Host

Mouse

Reactivity

Human

Immunogen

Ni-NTA purified truncated recombinant C-kit expressed in E. Coli strain BL21 (DE3) .

Clonality

Monoclonal

Clone

8D7B4 / 8D7D4 / 7H6B2 / 7H6B12

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Innate Immunity

Purification

Antibody is purified by protein A affinity chromatography.

Concentration

Batch dependent

Buffer

Ascitic fluid containing 0.03% sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

C-Kit monoclonal antibody can be stored at -20˚ C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.