CK1 Antibody [3C10F7 / 3C10G5 / PMC01 / 4D12B3]

Product Specifications

Background

CK1 (also designated Cytokeratin 1 or KRT1), with 644-amino acid protein (about 70 kDa), is a member of the keratin family. Cytokeratins play a critical role in differentiation and tissue specialization, and they function to maintain the overall structural integrity of epithelial cells.CK1 consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. CK1 is specifically expressed in the spinous and granular layers of the epidermis with family member KRT10 and mutations in these genes have been associated with bullous congenital ichthyosiform erythroderma.

NCBI Gene ID

1452

Swiss Prot

P48729

Accession Number

P48729

Host

Mouse

Reactivity

Human

Immunogen

Ni-NTA purified truncated recombinant CK1 expressed in E. Coli strain BL21 (DE3) .

Clonality

Monoclonal

Clone

3C10F7 / 3C10G5 / PMC01 / 4D12B3

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Concentration

Batch dependent

Buffer

Ascitic fluid containing 0.03% sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

CK1 monoclonal antibody can be stored at -20˚ C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.