CIB1 Antibody [5A1F5E12 / 5A1H7E12]

Product Specifications

Background

CIB1 (also designated calcium and integrin binding 1 or calmyrin), with 191-amino acid protein (about 21 kDa), belongs to the calcium-binding protein family.CIB1 is known to interact with DNA-dependent protein kinase and may play a role in kinase-phosphatase regulation of DNA end joining.CIB1 is an EF-hand-containing protein that binds multiple effector proteins, including the platelet alpha (IIb) beta (3) integrin and several serine/threonine kinases and potentially modulates their function.CIB1 regulates platelet aggregation in hemostasis through a specific interaction with the alpha (IIb) cytoplasmic domain of platelet integrin alpha (IIb) beta (3) . CIB1 is also ubiquitously expressed activating and inhibiting protein ligand of the InsP3R.

NCBI Gene ID

10519

Swiss Prot

Q99828

Accession Number

NP_001264693.1

Host

Mouse

Reactivity

Human

Immunogen

Ni-NTA purified truncated recombinant CIB1 expressed in E. Coli strain BL21 (DE3) .

Clonality

Monoclonal

Clone

5A1F5E12 / 5A1H7E12

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Concentration

Batch dependent

Buffer

Ascitic fluid containing 0.03% sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

CIB1 monoclonal antibody can be stored at -20˚ C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.