CD8 Antibody [RAVB3]
Product Specifications
Background
CD8 T cell surface antigen is heterodimer of an alpha and a beta chain linked by two disulfide bonds .It belongs type I membrane protein. Selectively expressing of CD8 on a subset of T cells leads to CD8 T cell development. Through identifying cytotoxic/suppressor T-cells that interact with MHC class I bearing targets, CD8 is thought to play a role in the process of T-cell mediated killing. Veillette et al (1988) found the CD8 is associated with the internal membrane tyrosine-protein kinase p56lck.
NCBI Gene ID
925
Swiss Prot
P01732
Accession Number
P01732
Host
Mouse
Reactivity
Human
Immunogen
Ni-NTA purified recombinant human CD8 expressed in E. Coli strain BL21 (DE3) .
Clonality
Monoclonal
Clone
RAVB3
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology
Purification
Antibody is purified by protein A affinity chromatography.
Concentration
Batch dependent
Buffer
Purified antibody in PBS containing 0.03% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
CD8 monoclonal antibody can be stored at -20˚ C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Fragment
IgG1
Symbol
CD8A
NCBI Official Name
CD8a molecule
NCBI Organism
Homo sapiens
Background Reference 01
Veillette, A. et al. 1988. Cell 55:301.
Other Product Names
MALCD8, MAL, p32, Leu2
Tested Applications
ELISA, WB
Protein ID
116035
Curated Selection
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