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BNP3 Antibody [3A6F7C7]

Product Specifications

Background

BNP (brain natriuretic peptide) belongs to a family of structurally similar peptide hormones, which includes atrial natriuretic peptide (ANP), BNP, C-type natriuretic peptide (CNP) and urodilatin. ANP and BNP act mainly as cardiac hormones, produced primarily by the atrium and ventricle, respectively, while the gene encoding C-type natriuretic peptide is expressed mainly in the brain. BNP circulates in blood as a peptide hormone with natriuretic, vasodilatory and renin inhibitory properties. It is secreted predominantly by the left ventricular myocytes in response to volume expansion and pressure overload. These peptides are characterized by a common 17 amino acid ring structure with a disulfide bond between two cystein residues. This ring structure shows high homology between different natriuretic.

NCBI Gene ID

4879

Swiss Prot

P16860

Accession Number

P16860

Host

Mouse

Reactivity

Human

Immunogen

Synthetic peptide corresponding to aa (Glu-Pro-Leu-Gln-Glu-Ser-Pro-Arg-Pro-Thr-Gly-Val-Trp-Cys) of human BNP3.

Clonality

Monoclonal

Clone

3A6F7C7

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Growth Factors

Concentration

Batch dependent

Buffer

Ascitic fluid containing 0.03% sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

BNP3 monoclonal antibody can be stored at -20˚ C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Fragment

IgG1

Symbol

NPPB

NCBI Official Name

Natriuretic peptide B

NCBI Organism

Homo sapiens

Background Reference 01

Dawson A. Struthers AD. Expert Opin Biol Ther. 2003, Feb, 3 (1) :107-12. Review.

Background Reference 02

Pfister R. Erdmann E. Schneider CA. Dtsch Med Wochenschr. 2003, May 2, 128 (18) :1007-12.

Other Product Names

Gamma-brain natriuretic peptide, BNP-32, BNP

Tested Applications

IHC

Protein ID

113836

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