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ApoM Antibody [8F12C6B8]

Product Specifications

Background

ApoM (apolipoprotein M, also designated G3a or NG20), with 188-amino acid protein (about 21 kDa), is an apolipoprotein and member of the lipocalin protein family.The Apo-proteins are involved in the specific binding of cellular receptors, the regulation of lipolytic enzymes, and the process of lipid exchange. The encoded protein is secreted through the plasma membrane but remains membrane-bound, where it is involved in lipid transport.The N-terminal region of Apo-M contains hydrophobic residues that may promote association with the phospholipid layer of lipoprotein particles. In vitro, Apo-M is glycosylated when translated in the presence of microsomes, and remains associated with the microsomes after carbonate treatment.Apo-M is expressed in liver and kidney, and is secreted into the bloodstream in HDLs, and also found in triglyceride-rich lipoproteins and LDLs.

NCBI Gene ID

55937

Swiss Prot

O95445

Accession Number

O95445

Host

Mouse

Reactivity

Human

Immunogen

Ni-NTA purified full-length recombinant ApoM.trx expressed in E. Coli strain BL21 (DE3) .

Clonality

Monoclonal

Clone

8F12C6B8

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

Antibody is purified by protein A affinity chromatography.

Concentration

Batch dependent

Buffer

Purified antibody in PBS containing 0.03% sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

ApoM monoclonal antibody can be stored at -20˚ C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Fragment

IgG1 & IgG2b

Symbol

APOM

NCBI Official Name

Apolipoprotein M

NCBI Organism

Homo sapiens

Background Reference 01

Xu, N. & Dahlback, B. 1999 J. Biol. Chem. 274:31286.

Background Reference 02

Duan J, Dahlback B, Villoutreix BO.FEBS Lett. 2001 Jun 15;499 (1-2) :127-32.

Background Reference 03

Xu, N., Nilsson-Ehle, P. & Ahren, B. 2004. J. Nutr.Biochem. 15 (10) :579-582.

Background Reference 04

Zhang, X.Y. , et al.2004. Acta Histochem. 106 (2) :123-128

Other Product Names

G3A, NG20, HSPC336, Protein G3a, Apo-M, G3a, apo-M

Tested Applications

ELISA, WB

Protein ID

17370872

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