Recombinant SARS-CoV-2 (COVID-19) Nucleocapsid ScFv Antibody [4A6]

Product Specifications

Background

Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. N protein packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.

NCBI Gene ID

43740575

Swiss Prot

P0DTC9

Accession Number

QHD43423

Reactivity

Virus

Immunogen

Full length recombinant Nucleocapsid Protein

Clonality

Recombinant Monoclonal

Clone

4A6

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Infectious Disease, COVID-19

Purification

≥95 %

Concentration

5.0 mg/ml (+/- 10 %)

Buffer

20mM PB, 150mM NaCl, pH 7.4.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

24 months from manufacturing at <-20 ˚ C; 1 month, 2 to 8 ˚ C under sterile conditions.

Specificity

Antibody recognizes 2019-nCoV Nucleocapsid Protein

Applications Notes

Immunoreactivity: 80-120 % compared to the reference sample in an ELISA test.

Symbol

NCBI Official Name

Nucleocapsid phosphoprotein

NCBI Organism

Severe acute respiratory syndrome coronavirus 2

Other Product Names

SARS-CoV-2 (COVID-19) Nucleocapsid Antibody: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Nucleocapsid protein, N protein, Nucleocapsid Phosphoprotein