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SPDYA Antibody

Product Specifications

Background

SPDYA (speedy homolog A (Drosophila) ) regulates the G1/S phase transition of the cell cycle by binding and activating CDC2, CDK2 and CDKN1B/KIP1. SPDYA can activate CDK2 without promoting CDK2 phosphorylation. SPDYA mediates cell survival during the DNA damage process through activation of CDK2.

NCBI Gene ID

245711

Swiss Prot

Q5MJ70

Accession Number

Q5MJ70

Host

Rabbit

Reactivity

Human

Immunogen

This SPDYA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 147-175 amino acids from the Central region of human SPDYA.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

36 kDa

Fragment

Rabbit Ig

Symbol

SPDYA

NCBI Official Name

Speedy protein A

NCBI Organism

Homo sapiens

Background Reference 01

Ke, Q., et al. Exp. Mol. Pathol. 87 (3) :167-172 (2009)

Background Reference 02

Dinarina, A., et al. FEBS Lett. 583 (17) :2772-2778 (2009)

Background Reference 03

McAndrew, C.W., et al. Cell Cycle 8 (1) :66-75 (2009)

Other Product Names

HGNC:30613

Tested Applications

WB, IHC-P, Flow

Protein ID

94730574

Physical Properties

Liquid

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