SPDYA Antibody
Product Specifications
Background
SPDYA (speedy homolog A (Drosophila) ) regulates the G1/S phase transition of the cell cycle by binding and activating CDC2, CDK2 and CDKN1B/KIP1. SPDYA can activate CDK2 without promoting CDK2 phosphorylation. SPDYA mediates cell survival during the DNA damage process through activation of CDK2.
NCBI Gene ID
245711
Swiss Prot
Q5MJ70
Accession Number
Q5MJ70
Host
Rabbit
Reactivity
Human
Immunogen
This SPDYA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 147-175 amino acids from the Central region of human SPDYA.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=64-220
Calculated Molecular Weight
36 kDa
Fragment
Rabbit Ig
Symbol
SPDYA
NCBI Official Name
Speedy protein A
NCBI Organism
Homo sapiens
Background Reference 01
Ke, Q., et al. Exp. Mol. Pathol. 87 (3) :167-172 (2009)
Background Reference 02
Dinarina, A., et al. FEBS Lett. 583 (17) :2772-2778 (2009)
Background Reference 03
McAndrew, C.W., et al. Cell Cycle 8 (1) :66-75 (2009)
Other Product Names
HGNC:30613
Tested Applications
WB, IHC-P, Flow
Protein ID
94730574
Physical Properties
Liquid
Curated Selection
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