DAZAP2 Antibody
Product Specifications
Background
DAZAP2 encodes a proline-rich protein which interacts with the deleted in azoospermia (DAZ) and the deleted in azoospermia-like gene through the DAZ-like repeats. This protein also interacts with the transforming growth factor-beta signaling molecule SARA (Smad anchor for receptor activation), eukaryotic initiation factor 4G, and an E3 ubiquitinase that regulates its stability in splicing factor containing nuclear speckles. The encoded protein may function in various biological and pathological processes including spermatogenesis, cell signaling and transcription regulation, formation of stress granules during translation arrest, RNA splicing, and pathogenesis of multiple myeloma.
NCBI Gene ID
9802
Swiss Prot
Q15038
Accession Number
Q15038
Host
Rabbit
Reactivity
Human
Immunogen
This DAZAP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 111-139 amino acids from the C-terminal region of human DAZAP2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
17 kDa
Fragment
Rabbit Ig
Symbol
DAZAP2
NCBI Official Name
DAZ-associated protein 2
NCBI Organism
Homo sapiens
Background Reference 01
Venkatesan, K., et al. Nat. Methods 6 (1) :83-90 (2009)
Background Reference 02
Kim, J.E., et al. Mol. Cell. Biol. 28 (2) :803-813 (2008)
Background Reference 03
Shi, Y.W., et al. Chin. Med. J. 120 (19) :1659-1665 (2007)
Other Product Names
DAZ-associated protein 2, Deleted in azoospermia-associated protein 2, DAZAP2, KIAA0058
Tested Applications
WB, IHC-P
Protein ID
44887865
Physical Properties
Liquid
Frequently Asked Questions
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