ALG10 Antibody
Product Specifications
Background
ALG10 encodes a membrane-associated protein that adds the third glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. That is, it transfers the terminal glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc2Man9GlcNAc (2) -PP-Dol. The rat protein homolog was shown to specifically modulate the gating function of the rat neuronal ether-a-go-go (EAG) potassium ion channel.
NCBI Gene ID
84920
Swiss Prot
Q5BKT4
Accession Number
Q5BKT4
Host
Rabbit
Reactivity
Human
Immunogen
This ALG10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 17-43 amino acids from the N-terminal region of human ALG10.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=64-208
Calculated Molecular Weight
56 kDa
Fragment
Rabbit Ig
Symbol
ALG10
NCBI Official Name
Dol-P-Glc:Glc (2) Man (9) GlcNAc (2) -PP-Dol alpha-1,2-glucosyltransferase
NCBI Organism
Homo sapiens
Background Reference 01
Chapuis, J., et al. Mol. Psychiatry 14 (11) :1004-1016 (2009)
Background Reference 02
Seshadri, S., et al. BMC Med. Genet.SUPPL 1, S15 (2007)
Background Reference 03
Kupershmidt, S., et al. FASEB J. 17 (15) :2263-2265 (2003)
Other Product Names
Dol-P-Glc:Glc (2) Man (9) GlcNAc (2) -PP-Dol alpha-1,2-glucosyltransferase, Alpha-1,2-glucosyltransferase ALG10-A, Alpha-2-glucosyltransferase ALG10-A, Asparagine-linked glycosylation protein 10 homolog A, ALG10, ALG10A
Tested Applications
WB, IHC-P
Protein ID
74736030
Physical Properties
Liquid
Curated Selection
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