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CIRH1A Antibody

Product Specifications

Background

CIRH1A encodes a WD40-repeat-containing protein that is localized to the nucleolus. Mutation of this gene causes North American Indian childhood cirrhosis, a severe intrahepatic cholestasis that results in transient neonatal jaundice, and progresses to periportal fibrosis and cirrhosis in childhood and adolescence.

NCBI Gene ID

84916

Swiss Prot

Q969X6

Accession Number

Q969X6

Host

Rabbit

Reactivity

Human

Immunogen

This CIRH1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 116-143 amino acids from the N-terminal region of human CIRH1A.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

77 kDa

Fragment

Rabbit Ig

Symbol

CIRH1A

NCBI Official Name

Cirhin

NCBI Organism

Homo sapiens

Background Reference 01

Yu, B., et al. Exp. Cell Res. 315 (18) :3086-3098 (2009) Carlton, V.E., et al. Ann. Med. 36 (8) :606-617 (2004)

Other Product Names

Cirhin, CIRH1A, KIAA1988, UTP4

Tested Applications

WB, IHC-P, Flow

Protein ID

41016916

Physical Properties

Liquid

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