CIRH1A Antibody
Product Specifications
Background
CIRH1A encodes a WD40-repeat-containing protein that is localized to the nucleolus. Mutation of this gene causes North American Indian childhood cirrhosis, a severe intrahepatic cholestasis that results in transient neonatal jaundice, and progresses to periportal fibrosis and cirrhosis in childhood and adolescence.
NCBI Gene ID
84916
Swiss Prot
Q969X6
Accession Number
Q969X6
Host
Rabbit
Reactivity
Human
Immunogen
This CIRH1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 116-143 amino acids from the N-terminal region of human CIRH1A.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
77 kDa
Fragment
Rabbit Ig
Symbol
CIRH1A
NCBI Official Name
Cirhin
NCBI Organism
Homo sapiens
Background Reference 01
Yu, B., et al. Exp. Cell Res. 315 (18) :3086-3098 (2009) Carlton, V.E., et al. Ann. Med. 36 (8) :606-617 (2004)
Other Product Names
Cirhin, CIRH1A, KIAA1988, UTP4
Tested Applications
WB, IHC-P, Flow
Protein ID
41016916
Physical Properties
Liquid
Curated Selection
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