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SNX27 Antibody

Product Specifications

Background

SNX27 encodes a member of the sorting nexin family, a diverse group of cytoplasmic and membrane-associated proteins involved in endocytosis of plasma membrane receptors and protein trafficking through these compartments. All members of this protein family contain a phosphoinositide binding domain (PX domain) . A highly similar protein in mouse is responsible for the specific recruitment of an isoform of serotonin 5-hydroxytryptamine 4 receptor into early endosomes, suggesting the analogous role for the human protein.

NCBI Gene ID

81609

Swiss Prot

Q96L92

Accession Number

Q96L92

Host

Rabbit

Reactivity

Human

Immunogen

This SNX27 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 313-340 amino acids from the Central region of human SNX27.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

61 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

SNX27

NCBI Official Name

Sorting nexin-27

NCBI Organism

Homo sapiens

Background Reference 01

Lunn, M.L., et al. Nat. Neurosci. 10 (10) :1249-1259 (2007)

Background Reference 02

Nassirpour, R., et al. Channels (Austin) 1 (5) :331-333 (2007)

Background Reference 03

MacNeil, A.J., et al. Biochem. Biophys. Res. Commun. 359 (4) :848-853 (2007)

Background Reference 04

Rincon, E., et al. Mol. Cell Proteomics 6 (6) :1073-1087 (2007)

Other Product Names

Sorting nexin-27, SNX27, KIAA0488

Tested Applications

WB

Protein ID

166214988

Physical Properties

Liquid

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