PYCR1 Antibody
Product Specifications
Background
This gene encodes an enzyme that catalyzes the NAD (P) H-dependent conversion of pyrroline-5-carboxylate to proline. This enzyme may also play a physiologic role in the generation of NADP (+) in some cell types. The protein forms a homopolymer and localizes to the mitochondrion.
NCBI Gene ID
5831
Swiss Prot
P32322
Accession Number
P32322
Host
Rabbit
Reactivity
Human
Immunogen
This PYCR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 291-319 amino acids from the C-terminal region of human PYCR1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
33 kDa
Fragment
Rabbit Ig
Symbol
PYCR1
NCBI Official Name
Pyrroline-5-carboxylate reductase 1, mitochondrial
NCBI Organism
Homo sapiens
Background Reference 01
Reversade, B., et al. Nat. Genet. 41 (9) :1016-1021 (2009)
Background Reference 02
Guernsey, D.L., et al. Am. J. Hum. Genet. 85 (1) :120-129 (2009)
Background Reference 03
Meng, Z., et al. J. Mol. Biol. 359 (5) :1364-1377 (2006)
Other Product Names
Pyrroline-5-carboxylate reductase 1, mitochondrial, P5C reductase 1, P5CR 1, PYCR1
Tested Applications
WB, IHC-P, Flow
Protein ID
60416434
Physical Properties
Liquid
Frequently Asked Questions
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