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PYCR1 Antibody

Product Specifications

Background

This gene encodes an enzyme that catalyzes the NAD (P) H-dependent conversion of pyrroline-5-carboxylate to proline. This enzyme may also play a physiologic role in the generation of NADP (+) in some cell types. The protein forms a homopolymer and localizes to the mitochondrion.

NCBI Gene ID

5831

Swiss Prot

P32322

Accession Number

P32322

Host

Rabbit

Reactivity

Human

Immunogen

This PYCR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 291-319 amino acids from the C-terminal region of human PYCR1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=64-173

Calculated Molecular Weight

33 kDa

Fragment

Rabbit Ig

Symbol

PYCR1

NCBI Official Name

Pyrroline-5-carboxylate reductase 1, mitochondrial

NCBI Organism

Homo sapiens

Background Reference 01

Reversade, B., et al. Nat. Genet. 41 (9) :1016-1021 (2009)

Background Reference 02

Guernsey, D.L., et al. Am. J. Hum. Genet. 85 (1) :120-129 (2009)

Background Reference 03

Meng, Z., et al. J. Mol. Biol. 359 (5) :1364-1377 (2006)

Other Product Names

Pyrroline-5-carboxylate reductase 1, mitochondrial, P5C reductase 1, P5CR 1, PYCR1

Tested Applications

WB, IHC-P, Flow

Protein ID

60416434

Physical Properties

Liquid

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