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HCCS Antibody

Product Specifications

Background

The protein encoded by this gene is an enzyme that covalently links a heme group to the apoprotein of cytochrome c. Defects in this gene are a cause of microphthalmia syndromic type 7 (MCOPS7) . Three transcript variants encoding the same protein have been found for this gene.

NCBI Gene ID

3052

Swiss Prot

P53701

Accession Number

P53701

Host

Rabbit

Reactivity

Human

Immunogen

This HCCS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 173-200 amino acids from the Central region of human HCCS.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Chicken

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

31 kDa

Fragment

Rabbit Ig

Symbol

HCCS

NCBI Official Name

Cytochrome c-type heme lyase

NCBI Organism

Homo sapiens

Background Reference 01

Need, A.C., et al. Hum. Mol. Genet. 18 (23) :4650-4661 (2009)

Background Reference 02

Wimplinger, I., et al. Mol. Vis. 13, 1475-1482 (2007)

Background Reference 03

Wimplinger, I., et al. Am. J. Hum. Genet. 79 (5) :878-889 (2006)

Background Reference 04

Nakashima-Kamimura, N., et al. J. Cell. Sci. 118 (PT 22), 5357-5367 (2005)

Other Product Names

Cytochrome c-type heme lyase, CCHL, Holocytochrome c-type synthase, HCCS, CCHL

Tested Applications

WB, IHC-P

Protein ID

1705694

Physical Properties

Liquid

Curated Selection

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