GTSE1 Antibody

Product Specifications

Background

GTSE1 is only expressed in the S and G2 phases of the cell cycle, where it colocalizes with cytoplasmic tubulin and microtubules. In response to DNA damage, the encoded protein accumulates in the nucleus and binds the tumor suppressor protein p53, shuttling it out of the nucleus and repressing its ability to induce apoptosis.

NCBI Gene ID

51512

Swiss Prot

Q9NYZ3

Accession Number

Q9NYZ3

Host

Rabbit

Reactivity

Human

Immunogen

This GTSE1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 690-717 amino acids from the C-terminal region of human GTSE1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

77 kDa

Fragment

Rabbit Ig

Symbol

GTSE1

NCBI Official Name

G2 and S phase-expressed protein 1

NCBI Organism

Homo sapiens

Background Reference 01

Bublik, D.R., et al. J. Biol. Chem. 285 (8) :5274-5281 (2010)

Background Reference 02

Beausoleil, S.A., et al. Nat. Biotechnol. 24 (10) :1285-1292 (2006)

Background Reference 03

Kapranov, P., et al. Genome Res. 15 (7) :987-997 (2005)

Background Reference 04

Cheng, J., et al. Science 308 (5725) :1149-1154 (2005)

Other Product Names

G2 and S phase-expressed protein 1, GTSE-1, Protein B99 homolog, GTSE1

Tested Applications

WB, IHC-P, Flow

Protein ID

317373439

Physical Properties

Liquid

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