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ADCY4 Antibody

Product Specifications

Background

This gene encodes a member of the family of adenylate cyclases, which are membrane-associated enzymes that catalyze the formation of the secondary messenger cyclic adenosine monophosphate (cAMP) . Mouse studies show that adenylate cyclase 4, along with adenylate cyclases 2 and 3, is expressed in olfactory cilia, suggesting that several different adenylate cyclases may couple to olfactory receptors and that there may be multiple receptor-mediated mechanisms for the generation of cAMP signals.

NCBI Gene ID

196883

Swiss Prot

Q8NFM4

Accession Number

Q8NFM4

Host

Rabbit

Reactivity

Human

Immunogen

This ADCY4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 415-441 amino acids from the Central region of human ADCY4.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

120 kDa

Fragment

Rabbit Ig

Symbol

ADCY4

NCBI Official Name

Adenylate cyclase type 4

NCBI Organism

Homo sapiens

Background Reference 01

Rhim, J.H., et al. Aging Cell 5 (6) :451-461 (2006)

Background Reference 02

Jiang, G., et al. Am. J. Physiol. Endocrinol. Metab. 284 (4), E671-E678 (2003)

Background Reference 03

Sunahara, R.K., et al. Mol. Interv. 2 (3) :168-184 (2002)

Background Reference 04

Ludwig, M.G., et al. J. Recept. Signal Transduct. Res. 22 (1-4), 79-110 (2002)

Other Product Names

Adenylate cyclase type 4, ATP pyrophosphate-lyase 4, Adenylate cyclase type IV, Adenylyl cyclase 4, ADCY4

Tested Applications

WB, Flow

Protein ID

25008336

Physical Properties

Liquid

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