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K2C78 Antibody

Product Specifications

Background

This gene is a member of the type II keratin gene family and encodes a protein with an intermediate filament domain. Keratins are the major structural proteins in epithelial cells, forming a cytoplasmic network of 10 to 12 nm wide intermediate filaments and creating a scaffold that gives cells the ability to withstand mechanical and non-mechanical stresses. The genes of the type II keratin family are located as a gene cluster at 12p13.13. Four pseudogenes of this gene family have been identified.

NCBI Gene ID

196374

Swiss Prot

Q8N1N4

Accession Number

Q8N1N4

Host

Rabbit

Reactivity

Human

Immunogen

This K2C78 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 176-203 amino acids from the Central region of human K2C78.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

57 kDa

Fragment

Rabbit Ig

Symbol

KRT78

NCBI Official Name

Keratin, type II cytoskeletal 78

NCBI Organism

Homo sapiens

Background Reference 01

Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007)

Background Reference 02

Schweizer, J., et al. J. Cell Biol. 174 (2) :169-174 (2006)

Background Reference 03

Rogers, M.A., et al. J. Invest. Dermatol. 124 (3) :536-544 (2005)

Background Reference 04

Hesse, M., et al. Eur. J. Cell Biol. 83 (1) :19-26 (2004)

Other Product Names

Keratin, type II cytoskeletal 78, Cytokeratin-78, CK-78, Keratin-5b, Keratin-78, K78, Type-II keratin Kb40, KRT78, K5B, KB40

Tested Applications

WB, Flow

Protein ID

166218809

Physical Properties

Liquid

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