FCRL4 Antibody
Product Specifications
Background
This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein has four extracellular C2-type immunoglobulin domains, a transmembrane domain and a cytoplasmic domain that contains three immune-receptor tyrosine-based inhibitory motifs. This protein may play a role in the function of memory B-cells in the epithelia. Aberrations in the chromosomal region encoding this gene are associated with non-Hodgkin lymphoma and multiple myeloma.
NCBI Gene ID
83417
Swiss Prot
Q96PJ5
Accession Number
Q96PJ5
Host
Rabbit
Reactivity
Human
Immunogen
This FCRL4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 480-507 amino acids from the C-terminal region of human FCRL4.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=64-144
Calculated Molecular Weight
57 kDa
Fragment
Rabbit Ig
Symbol
FCRL4
NCBI Official Name
Fc receptor-like protein 4
NCBI Organism
Homo sapiens
Background Reference 01
Davila, S., et al. Genes Immun. (2010) In press :
Background Reference 02
Weiss, G.E., et al. J. Immunol. 183 (3) :2176-2182 (2009)
Background Reference 03
Kazemi, T., et al. Cancer Immunol. Immunother. 58 (6) :989-996 (2009)
Background Reference 04
Falini, B., et al. Blood 102 (10) :3684-3692 (2003)
Other Product Names
Fc receptor-like protein 4, FcR-like protein 4, FcRL4, Fc receptor homolog 4, FcRH4, IFGP family protein 2, hIFGP2, Immune receptor translocation-associated protein 1, CD307d, FCRL4, FCRH4, IFGP2, IRTA1
Tested Applications
WB, Flow
Protein ID
74761029
Physical Properties
Liquid
Curated Selection
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