FCRL4 Antibody

Product Specifications

Background

This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein has four extracellular C2-type immunoglobulin domains, a transmembrane domain and a cytoplasmic domain that contains three immune-receptor tyrosine-based inhibitory motifs. This protein may play a role in the function of memory B-cells in the epithelia. Aberrations in the chromosomal region encoding this gene are associated with non-Hodgkin lymphoma and multiple myeloma.

NCBI Gene ID

83417

Swiss Prot

Q96PJ5

Accession Number

Q96PJ5

Host

Rabbit

Reactivity

Human

Immunogen

This FCRL4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 480-507 amino acids from the C-terminal region of human FCRL4.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

57 kDa

Fragment

Rabbit Ig

Symbol

FCRL4

NCBI Official Name

Fc receptor-like protein 4

NCBI Organism

Homo sapiens

Background Reference 01

Davila, S., et al. Genes Immun. (2010) In press :

Background Reference 02

Weiss, G.E., et al. J. Immunol. 183 (3) :2176-2182 (2009)

Background Reference 03

Kazemi, T., et al. Cancer Immunol. Immunother. 58 (6) :989-996 (2009)

Background Reference 04

Falini, B., et al. Blood 102 (10) :3684-3692 (2003)

Other Product Names

Fc receptor-like protein 4, FcR-like protein 4, FcRL4, Fc receptor homolog 4, FcRH4, IFGP family protein 2, hIFGP2, Immune receptor translocation-associated protein 1, CD307d, FCRL4, FCRH4, IFGP2, IRTA1