ADAM19 Antibody
Product Specifications
Background
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This member is a type I transmembrane protein and serves as a marker for dendritic cell differentiation. It has also been demonstrated to be an active metalloproteinase, which may be involved in normal physiological and pathological processes such as cells migration, cell adhesion, cell-cell and cell-matrix interactions, and signal transduction.
NCBI Gene ID
8728
Swiss Prot
Q9H013
Accession Number
Q9H013
Host
Rabbit
Reactivity
Human
Immunogen
This ADAM19 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 207-236 amino acids from the Central region of human ADAM19.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
105 kDa
Fragment
Rabbit Ig
Symbol
ADAM19
NCBI Official Name
Disintegrin and metalloproteinase domain-containing protein 19
NCBI Organism
Homo sapiens
Background Reference 01
Hancock, D.B., et al. Nat. Genet. 42 (1) :45-52 (2010)
Background Reference 02
Styrkarsdottir, U., et al. Nat. Genet. 41 (1) :15-17 (2009)
Background Reference 03
Chan, M.W., et al. Neoplasia 10 (9) :908-919 (2008)
Background Reference 04
Tanabe, C., et al. Biochem. Biophys. Res. Commun. 352 (1) :111-117 (2007)
Other Product Names
Disintegrin and metalloproteinase domain-containing protein 19, ADAM 19, 3424-, Meltrin-beta, Metalloprotease and disintegrin dendritic antigen marker, MADDAM, ADAM19, MLTNB
Tested Applications
WB, IHC-P, Flow
Protein ID
302393821
Physical Properties
Liquid
Curated Selection
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